Sinaflan (fluocinolone acetonide) ointment 0.025% 15 g.


Seborrheic dermatitis; atopic dermatitis; urticaria lichen; contact allergic eczema; polymorphic erythema; lupus tuberculosis; psoriasis; lichen planus.

Category: Manufacturer: Russia


Composition and form of release
The main active ingredient: 1 g of the drug contains 0.25 mg of fluocinolone acetonide.
Excipients: propylene glycol, petroleum jelly, lanolin, solid paraffin.
Pharmacological properties
This drug is classified as a corticosteroid for use in dermatology.
The active ingredient, fluocinolone acetonide, is an effective synthetic glucocorticosteroid for external use. It exhibits pronounced anti-inflammatory, anti-allergic, anti-allergic and vasoconstrictor effects. Also, the active substance has a lipophilic property and is easily absorbed through the skin.
Immediately after applying 2 g of the drug, the production of ACTH (ACTH) by the pituitary gland may decrease. This effect is due to the suppression of the adrenal gland-pituitary gland system. The drug undergoes transformation in the liver. Elimination from the body occurs in the urine.
The drug is prescribed in the following cases:

  • psoriasis;
  • lichen planus;
  • seborrheic dermatitis;
  • eczema of various origins and localization (including eczema in children);
  • neurodermatitis;
  • itching of various origins;
  • allergic skin diseases;
  • discoid lupus erythematosus;
  • 1st degree burns;
  • sunburn;
  • insect bites.

The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.
The drug is contraindicated in the following cases:

  • bacterial, viral, fungal skin diseases;
  • lupus;
  • cutaneous manifestations of syphilis;
  • extensive psoriatic plaques;
  • anogenital itching;
  • trophic ulcers of the leg associated with varicose veins;
  • skin tumors.

The drug is used in pediatrics after 2 years.
Application during pregnancy and lactation
This drug is contraindicated for pregnant women – only under strict indications determined by the attending physician.
If you need to take the drug during breastfeeding, you should stop lactation.
Method of administration and dosage
The drug is applied in a thin layer to the affected skin area 1-2 times a day.
The ointment should not be applied under an occlusive dressing. In the case of psoriasis, a closed dressing is allowed, which should be changed every day.
Treatment should not be carried out longer than 2 weeks.
Do not use on the face for more than 1 week. It is recommended to use no more than 15 g of ointment (1 tube) throughout the week.
In case of an overdose of the drug, the following phenomena may occur:

  • burning sensation at the site of application of the drug;
  • glucosuria;
  • swelling;
  • arterial hypertension;
  • decrease in the body’s resistance to infections.

Side effects
The drug is usually well tolerated when used in the recommended doses.
As side effects can be observed:

  • telangiectasia;
  • post-steroidal vascular purpura;
  • skin atrophy;
  • stretching of the skin;
  • hirsutism;
  • hypertrichosis;
  • perioral dermatitis;
  • secondary infectious skin lesions;
  • with prolonged use and / or when applied to large surfaces, systemic side effects are possible.

Storage conditions and periods
Expiration date – up to 2 years from the production date indicated on the package. Storage periods should not be exceeded.
Storage temperature should not exceed 25 ° C. Temperature deviations can change the properties of the preparation, therefore it should always be stored in its original packaging.