Spazmalgon (metamizole sodium) tablets №20


Symptomatic treatment of mild to moderate pain syndrome with spasms of smooth muscles of internal organs: renal colic and inflammatory diseases of the urinary tract, accompanied by pain and dysuric disorders; cramps of the stomach and intestines, hepatic colic, biliary dyskinesia; spastic dysmenorrhea.



Composition and form of release
The active components of the drug Spazmalgon are fenpiverinium bromide, metamizole sodium, pitofenone hydrochloride.
This drug is available in the form of tablets.
The drug Spazmalgon is a combined antispasmodic agent that has the following pharmacological actions: antipyretic (antipyretic), analgesic (analgesic), antispasmodic (eliminates smooth muscle spasm), as well as some anti-inflammatory.
Metamizole sodium has pronounced analgesic and antipyretic effects, and also has less pronounced antispasmodic and anti-inflammatory activities.
Fenpiverinium helps to reduce motility and tone of smooth muscles of the biliary tract, intestines, stomach and urinary tract.
Pitofenone has a pronounced antispasmodic effect, acting on the smooth muscles of the internal organs and blood vessels.
The drug Spazmalgon is used for the symptomatic treatment of moderate and mild pain syndrome against a background of smooth muscle spasm of internal organs. Spazmalgon is indicated for renal colic, spastic dysmenorrhea, inflammatory processes in the urinary tract, which are accompanied by pain and urinary disorders (dysuria), intestinal and stomach cramps, biliary dyskinesia, hepatic colic.
It is forbidden to use the drug Spazmalgon in case of hypersensitivity to any of its components, pyrazolone derivatives, intestinal obstruction, gallbladder atony, megacolone, severe renal and / or liver dysfunction, bladder atony, pathological changes in blood composition (for example, with agranulocytosis, leukopenia) , deficiency of the enzyme glucose-6-phosphate dehydrogenase, blood diseases (anemia of any origin, neutropenia), porphyria, bronchial asthma, tachyarrhythmias, angle-closure glaucoma, collaptoid conditions, prostatic hypertrophy with a tendency to retention (retention) of urine.
This drug is not used if the patient is suspected of having an acute surgical pathology (eg, appendicitis).
It is forbidden to prescribe the drug Spazmalgon to children under fifteen years of age.
The simultaneous use of Spazmalgon with medications that inhibit the work of the brain is prohibited.
Do not drink alcohol while using this drug.
You can not simultaneously take Spazmalgon and other drugs that contain metamizole.
This drug in tablet form is not recommended for use in patients suffering from celiac disease, lactase deficiency, galactose intolerance, and glucose-galactose malabsorption syndrome.
Use caution when using this drug in patients with hyperthyroidism.
Caution is also required by the use of Spazmalgon in patients with a history of allergic hypersensitivity to non-narcotic analgesics, NSAIDs.
Application during pregnancy and lactation
The drug Spazmalgon is prohibited for use in women during these periods.
Method of administration and dosage
Spazmalgon tablets are taken orally after meals with water.
The recommended doses for children over fifteen years of age and adults are 1-2 tablets / day, the maximum dose of this drug is 2 tablets / day.
The duration of the use of Spazmalgon tablets cannot exceed more than three days.

In case of an overdose of the drug Spazmalgon, impaired hepatic and / or renal function, respiratory paralysis may develop. Most often, gastrointestinal disorders occur, signs of hematopoiesis disorders, toxic-allergic syndrome appear, in severe cases of overdose, symptoms of brain damage may appear.
In case of suspicion of an overdose of this drug, it is necessary to immediately stop its intake into the body and take measures to quickly eliminate it. So, you should induce vomiting and carry out gastric lavage in case of an overdose with the drug in tablet form. It is also recommended to increase urine output (urine output).
In general, in case of an overdose of this drug, symptomatic therapy is carried out. There is no specific antidote.
Side effects
Against the background of the use of Spazmalgon, the development of allergic reactions of varying severity is possible. So, urticaria, itching, skin rashes, allergic conjunctivitis, toxic epidermal necrolysis, bronchospasm, angioedema, anaphylactic shock, Stevens-Johnson syndrome can occur.
Also, side effects that may occur with the use of Spazmalgon include dry mouth, abdominal discomfort, constipation, exacerbation of gastritis or gastric / duodenal ulcer, palpitation (abnormal, increased heartbeat), lowering blood pressure, tachycardia and others cardiac arrhythmias, the development of acute renal failure, dizziness, hematopoiesis disorders (for example, granulocytopenia, leukopenia, agranulocytosis, anemia, thrombocytopenia), oliguria (decreased urine production), anuria (no urine excretion), hepatitis, proteinuria (presence of protein in the urine ), interstitial nephritis, visual impairment, decreased sweating.
The metabolic products of the active component of Spazmalgon – metamizole sodium – can change the color of excreted urine to red. This phenomenon has no clinical significance.
Storage conditions and periods
Spazmalgon tablets and solution for intramuscular administration should be stored in a place protected from moisture and light. Storage temperature should not exceed + 25 ° С. The shelf life of the tablet form of this drug is two years. The shelf life of the injection solution is four years.
Spazmalgon must be stored out of the reach of children.