Congestive heart failure in patients who do not respond to treatment with other diuretics, or, if necessary, potentiate their effects. Essential arterial hypertension, mainly in the case of hypokalemia (usually in combination with other antihypertensive drugs). Cirrhosis of the liver, accompanied by edema and / or ascites. Initial hyperaldosteronism. Edema due to nephrotic syndrome. Hypokalemia, in case of impossibility of receiving another therapy. The drug is used to prevent hypokalemia in patients receiving cardiac glycosides, if other approaches are considered inappropriate or inappropriate.