Primary hyperaldosteronism. Congestive heart failure with inefficiency or intolerance of other diuretics or, if necessary, increase their effectiveness. Essential arterial hypertension, mainly with hypokalemia, usually in combination with other antihypertensive drugs. Cirrhosis of the liver, accompanied by edema and / or ascites. Edema due to nephrotic syndrome. Hypokalemia in case of impossibility of using other therapy. Prevention of hypokalemia for patients receiving cardiac glycosides, when other methods of therapy are considered inappropriate or inappropriate.