Sulperazon (sulbactam/cefoperazone) powder for injections 500 mg/500 mg. 1g. vial №1

$32.90

The drug is used to treat infections caused by susceptible strains of microorganisms: respiratory tract infections (upper and lower parts); urinary tract infections (upper and lower divisions); peritonitis, cholecystitis, cholangitis and other infections of the abdominal cavity; septicemia; meningitis; skin and soft tissue infections; infections of bones and joints; pelvic inflammatory diseases, endometritis, gonorrhea and other genital infections.

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Description

Composition and form of release
Consists of a combination of two active ingredients – cefoperazone and sulbactam. It is produced in the form of a lyophilized powder for injection, packaged in glass vials.
Indications
An antibiotic with a pronounced bactericidal effect. It is used as a medicine for infectious diseases of various organs, for example, for the treatment of infections of the respiratory and genitourinary systems. In addition, the drug is effective if the abdominal and pelvic organs, skin and soft tissues, the musculoskeletal system are affected by infections, as well as in meningitis and septicemia.
It has a pronounced bactericidal effect due to active active ingredients – sulbactam, which contains a penicillin nucleus and has the ability to irreversibly inhibit beta-lactamase and cefoperazou, a synthetic antibiotic of the cephalosporin group, capable of inhibiting the synthesis of mucopeptides of microorganism cell membranes. Due to the presence of sulbactam, the activity of the drug is 400% higher than that of pure cefoperazone. In general, the drug is active against gram-positive and gram-negative aerobic and anaerobic bacteria.
Contraindications
It is not prescribed for an allergic reaction to one of the active substances of the drug.
It should be prescribed with caution if the patient is diagnosed with impaired renal or liver function, obstructive diseases of the urinary tract, as well as patients who have been taking parenteral nutrition and anticoagulant treatment for a long time. Contains sodium salts, which should be taken into account with a specific low-sodium diet.
It is prescribed with caution in pediatrics.
Application during pregnancy and lactation
There are no recorded data on the safety of the use of this pharmaceutical product in the treatment of pregnant women. If there is a need for its use during the period when a woman is breastfeeding, lactation should be stopped at this time.
Method of administration and dosage
The drug is administered intramuscularly (with lidocaine, since the introduction is painful), intravenously (no faster than 3 minutes) and intravenous infusion (drip) – 15-60 minutes). The introduction is carried out by appropriately qualified medical personnel. Methods for preparing the solution are contained in the specialized medical literature. Adults are usually given 1 to 2 grams of the drug 12 hours apart. In severe infections, the dose can be doubled.
For kidney problems, the minimum dosage of 2 grams per day should not be exceeded.
A more accurate dosage and duration of treatment is prescribed by the attending physician.
Overdose
There have been no cases of overdose with Sulperazon. In this situation, symptoms should be treated. Hemodialysis is indicated for patients suffering from kidney disease. No antidote has yet been identified.
Side effects
Usually the drug is well tolerated by patients. Possible reactions from the gastrointestinal tract (nausea, vomiting, colitis). The development of jaundice, hyperbilirubinemia is possible.
The composition of the blood may change, in some cases the development of eosinophilia, neutropenia, leukopenia, a decrease in hemoglobin, and a decrease in the period of blood coagulation were noted. Blood pressure may rise.
Allergic skin reactions (pruritus, urticaria) have been reported. There were isolated cases of anaphylactic shock.
Storage conditions and periods
The drug is stored for up to 2 years in a dark place at a temperature of 15 to 25 ° C.