Terbizil cream 1% 15 g. tube


Fungal infections of the skin caused by dermatophytes of the genus Trichophyton (T. rubrum, T. mentagrophytes, T. verrucosum, T. violaceum), Microsporum Canis and Epidermophyton floccosum, for example, foot dermatophytes; inguinal dermatophytia (“itchy jockey”); dermatophytosis of the trunk (ringworm); candidiasis of the skin caused by fungi of the genus Candida, usually Candida albicans; multicolored lichen (Pityriasis versicolor) caused by Pityrosporum orbiculare, also known as Malassezia furfur.



Composition and form of release
Main active ingredient: terbinafine hydrochloride.
Excipients included in the preparation: sodium hydroxide, benzyl alcohol, cetyl and stearyl alcohol, sorbitan stearate, cetyl palmitate, polysorbate, isopropyl myristate, purified water.
It is produced in the form of a cream, in tubes with a volume of 15 grams, 10 mg of terbinafine in 1 gram of cream.
Pharmacological properties
This drug is included in the group of drugs for the treatment of mycoses.
The main active component of terbinafine is synthetic allylamine, which is highly effective against various dermatophyte fungi.
In particular, it is active against trichophytosis, tonsurans, verrucosum, microsporum, pityrosporum, candida, epidermophytosis, and other types of dermatophyte fungi.
When used in small doses, it has a fungicidal effect against dimorphic, mold and dermatophytes.
Relative to Candida fungi, it produces both fungicidal and fungistatic effects.
Able to influence the early stage of biosynthesis of one of the most important components of fungal cell membranes – ergosterols. As a result, there is a shortage of egosterols and the accumulation of squalene inside the cell. As a result, the death of the fungal cell occurs.
It has a low degree of absorption into the body.
This drug is used to treat:

  • fungal infections of the skin (trichophytosis of smooth skin and inguinal epidermophytosis), athlete’s feet (athlete’s foot);
  • fungal skin infections caused by yeast (cutaneous candidiasis);
  • multi-colored lichen.

The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components, hereditary fructose / maltose intolerance.
Contact with eyes should be avoided.
In pediatrics, it is used upon reaching the age of two.
Application during pregnancy and lactation
This drug is contraindicated for pregnant women.
If it is necessary to take the drug during breastfeeding, lactation is suspended.
Method of administration and dosage
The drug is used externally, applying it in a thin layer to thoroughly cleansed and dried skin (its affected by the fungus area), 1-2 times a day (depending on the type of disease and the strain of the fungus).
The cream is lightly rubbed both into the place of spread of the fungus, and capturing 1-2 cm around the affected skin.
If the skin is affected by a disease in the chest, groin, fingers, then after applying the cream, this place should be covered with gauze, gauze bandage (especially before going to bed).
Recommended courses of treatment:

  • trichophytosis of smooth skin and inguinal epidermophytosis – 2 times a day, period – 1 week;
  • athlete’s foot – 1-2 times a day, period – 1 week;
  • candidiasis of the skin – 1-2 times a day, period – 2 weeks;
  • versicolor versicolor – 1-2 times a day – 2 weeks.

If the effect is not noticeable within two weeks, the attending physician should be notified for re-evaluation of the diagnosis. If there is a need to continue the course of treatment, this can be done by the attending physician.
The faster you start taking the drug at the first signs of illness, the better the result.
Old age, liver or kidney disease are not reasons for adjusting the dosage, frequency or duration of treatment.
Overdose (when applied topically) is unlikely due to low absorption of the drug through the skin.
If the cream is accidentally swallowed, you may experience:

  • headache;
  • abdominal pain;
  • dizziness.

In this case, the symptoms should be treated – rinse the stomach, take enterosorbents.
When applied topically, itching and burning may occur, which quickly pass and do not require special treatment.
Side effects
The drug is usually well tolerated when used in the recommended doses.

Allergy may occur in case of individual intolerance. In particular, it can be observed:

  • allergic reactions – itching, allergic urticaria, rash;
  • burning of the skin at the site of application.

Storage conditions and periods
The shelf life is 5 years.
The storage temperature should not exceed 30 ° C.