Infectious and inflammatory diseases caused by microorganisms sensitive to the drug, such as bronchitis, pneumonia, bacterial and amoebic dysentery, gonorrhea, brucellosis, tularemia, rash and relapsing fever, psittacosis, ornithosis, biliary and urinary tract infections, purulent meningitis and soft tissues, cholera. Prevention of postoperative infections.
Composition and form of release
Tetracycline is available in tablets. The active ingredient of the drug is tetracycline hydrochloride.
Tetracycline is used in therapy of inflammatory and infectious diseases caused by tetracycline-sensitive microflora, such as bronchitis, pneumonia, tonsillitis, pleural empyema, cholecystitis, pyelonephritis, intestinal infection, endometritis, endocarditis, syphilis, prostatitis, brucellosis, gonorrhea, pus rickettsioses, trachoma, osteomyelitis, blepharitis, conjunctivitis, acne.
In addition, the drug is used to prevent the development of postoperative infectious complications.
Tetracycline is not prescribed for patients who have been identified as hypersensitive to tetracycline hydrochloride and related antibiotics. The drug is not used in the treatment of fungal infections and is not prescribed for pregnant and lactating women.
Particular care should be taken when prescribing the drug to patients who have renal failure, leukopenia and have a history of allergic reactions.
Due to the fact that strains resistant to tetracycline have been widespread recently, the drug is used very rarely.
Tetracycline is not used for children under 8 years of age because it can cause permanent discoloration of the tooth enamel.
When taking tetracycline for the prevention of hypovitaminosis, patients should take vitamins of groups K and B.
At the time of treatment with Tetracycline, the patient should refuse to use dairy products, since they prevent the adsorption of the antibiotic.
Application during pregnancy and lactation
Due to the fact that tetracycline hydrochloride is able to penetrate the placental barrier and cause hypoplasia of tooth enamel, inhibit the growth of bones of the fetal skeleton and change the color of the teeth for a long time and cause the development of fatty infiltration of the liver tissue, the use of tetracycline in the therapy of women at the stage of lactation and pregnancy is impossible.
Method of administration and dosage
Tetracycline is taken orally at 250 or 500 mg every 6 hours. The highest daily dose for adults is 4 g. Children who have turned 8 years old are prescribed the drug at 25 or 50 mg per kg of body weight every 6 hours.
With oral administration of tetracycline in high doses, patients experience increased side effects. With local application of the drug, an overdose is impossible.
In some patients, when taking tetracycline, there is the development of nausea, vomiting, abdominal pain, anorexia, stool disorders, dry mouth, glossitis, esophagitis, discoloration of teeth and tongue, increased activity of liver enzymes, dizziness, headaches, anemia, photosensitization and allergic reactions …
Storage conditions and periods
Store tetracycline in a cool place, protected from light and children. The term of storage of the drug is 3 years.