Symptomatic treatment of constipation. Osmotic laxatives.
Composition and form of release
The main active ingredient of the drug is lactulose, paraffin, mineral oil.
Excipients: aspartame, cholesterol, lactic acid, bixin oil, tangerine oil, lemon oil, and orange oil.
It is produced in the form of a paste for oral administration. It goes on sale packaged in jars with a volume of 150 ml of paste.
There are 35 grams of lactulose, 21.45 grams of white soft paraffin and 42.91 grams of mineral oil per 100 grams of paste.
This drug belongs to the group of osmotic laxative drugs used in gastroenterology.
The main active ingredient is lactulose, which has the property of being broken down in the intestine by intestinal bacteria. As a result of these processes, it turns into low molecular weight organic acids.
The latter cause a decrease in acidity in the colon, increasing the volume of its contents and exerting an osmotic effect. Due to the normalization of the consistency of feces, the motility of the large intestine is stimulated, constipation is corrected, the physiological digestive rhythm and the rhythm of bowel emptying are restored.
Lactulose also acts as a prebiotic, increasing the number of beneficial bacteria in the gut, specifically bifidobacteria and lactobacilli. It also inhibits the growth of bacteria that may be pathogenic, such as Clostridium or E. coli. Thus, the balance of intestinal microflora is normalized.
This drug is used to treat constipation of various etiologies.
In particular, it is used for:
- regulation of the physiological rhythm of the intestine with constipation;
- treatment of conditions requiring relief of bowel movements (hemorrhoids, conditions after operations on the large intestine and anorectal zone;
- treatment of portosystemic hepatic encephalopathy – treatment and prevention of hepatic coma and precoma.
Do not apply if the patient has hypersensitivity (allergy).
Also, use is contraindicated for:
- galactosemia, phenylketonuria;
- intestinal obstruction;
- perforation of the digestive tract;
- the risk of perforation of the digestive tract.
It is not used in pediatrics.
Application during pregnancy and lactation
This drug can be used during pregnancy and during breastfeeding, since the systemic effect of lactulose on a pregnant woman is insignificant. Also, no consequences for the fetus are expected.
Method of administration and dosage
Transulose is usually taken in the evening with a little water.
The dose and regimen of the drug should be adjusted in accordance with the needs of the patient.
During therapy with laxatives, it is recommended to consume a sufficient amount of liquid (1.5-2 liters per day, which corresponds to 8-10 glasses).
The recommended daily dosage is 1-3 scoops, once a day.
You should not take the drug while lying down or just before going to bed.
The duration of the course of treatment is no more than 8 days.
Elderly patients, as well as patients suffering from renal or hepatic insufficiency, do not need dosage adjustment.
When taking excessive dosages, the patient may experience:
- abdominal pain;
It is recommended to stop taking the drug or reduce the dosage, correct electrolyte imbalance in case of excessive fluid loss, which may be caused by diarrhea or vomiting.
Therapy with this drug can cause adverse reactions, especially at the beginning of treatment. Among them were observed:
- abdominal pain, diarrhea (if the recommended dosage is exceeded);
- possible discomfort, itching in the anus;
- slight decrease in body weight.
When using large therapeutic dosages, used for a long time, electrolyte imbalance may occur (due to prolonged significant dilution of the stool, diarrhea). Most often, this effect is observed in patients with hepatic insufficiency and encephalopathy, which should be taken into account in the treatment process.
In case of any unusual side effects, you should consult your doctor to adjust the course of treatment.
Storage conditions and periods
The shelf life of the drug is no more than 3 years from the production date indicated on the package.
Store in a dry place out of the reach of children, at a temperature not exceeding 30 ° C.