Means for use in ophthalmology. Anti-glaucoma drugs and myotics. Prostaglandin analogues. To reduce high intraocular pressure in patients with ocular hypertension or open-angle glaucoma. To reduce high intraocular pressure in children from 2 months to 18 years with ocular hypertension or pediatric glaucoma.
Composition and form of release
Main active ingredients: 1 ml of the drug contains 0.04 mg of travoprost.
Auxiliary components: benzalkonium chloride, sodium edetate, polyethoxylated, hydrogenated castor oil, tromethamine, boric acid, mannitol, concentrated hydrochloric acid, sodium hydroxide, water for injection.
The specified drug belongs to a group of drugs used in ophthalmology for the treatment of glaucoma.
The drug is a miotic, an analogue of F2-prostaglandin.
The active substance is its full selective agonist, with a high degree of affinity with the FP-receptors of prostaglandin.
The drug lowers intraocular hypertension, increases the outflow of fluid along the trabecular meshwork and uveoscleral pathway.
The hypotensive effect is observed within 2 hours after using the product. The best result is observed after 12 hours.
A significant decrease in pressure inside the eyes after using a single dose persists for more than 24 hours. Combination therapy with timolol 0.5% and brimonidine 0.2% potentiates the effect of the described drug.
The research results indicate blood flow to the optic nerve after 7 days of drug use.
The drug is prescribed to reduce intraocular pressure in ocular hypertension or open-angle glaucoma.
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.
The drug is not used in pediatrics.
Application during pregnancy and lactation
This drug is not recommended for pregnant women – only for strict indications determined by the attending physician.
If it is necessary to take the drug during breastfeeding, lactation is suspended.
Women of childbearing age should use contraceptive methods while using the drug.
Method of administration and dosage
The drug is used 1 drop in the conjunctival sac of the affected eye 1 time per day. The best effect is achieved when the drug is administered in the evening.
After instillation, nasolacrimal occlusion or light eyelid closure is recommended.
When using more than one ophthalmic agent for topical application, the time interval should be at least 5 minutes.
In case of local drug overdose, rinse the eye with warm water.
If medication is accidentally swallowed, symptomatic and supportive therapy is performed.
The drug is usually well tolerated if used in the recommended doses and the regimen is followed.
Allergy may occur in case of individual intolerance. In particular, there may be observed:
- herpetic keratitis;
- acupuncture keratitis, precipitates in the anterior chamber of the eye, opalescence in the anterior chamber of the eye, eye pain, photophobia, discharge from the eye, sensation of discomfort in the eye, eye irritation, abnormal sensitivity of the eyes, sensation of a foreign body in the eye, decreased visual acuity, blurred vision, dry eyes, itchy eyes, increased lacrimation, erythema of the eyelids, edema of the eyelids, itching of the eyelids, eyelash growth, eyelash discoloration;
- irregular heart rate, increased heart rate, decreased heart rate;
- lowering blood pressure, increasing blood pressure, arterial hypotension or hypertension.
Storage conditions and periods
Expiration date – up to 2 years from the production date indicated on the package. Storage periods should not be exceeded.
Storage temperature should not exceed 25 ° C. Temperature deviations can change the properties of the preparation, therefore it should always be stored in its original packaging.