Triacutan ointment 15 g. tube


Treatment of dermatoses sensitive to glucocorticoids in the presence (or suspicion) of bacterial and / or fungal infections caused by microorganisms sensitive to the drug.



Triacutan Composition and form of release
The main active drugs are betamethasone, gentamicin, clotrimazole.
Auxiliary components are: methylparaben, propylene glycol, mineral oil, white soft paraffin, cetostearyl alcohol, macrogol, cetostearyl ether, sodium dihydrogen phosphate monohydrate, sodium phosphate, dodecahydrate purified water.
It is produced in the form of a medicinal cream, packed in tubes of 15 grams each, where 1 gram of cream contains 0.64 mg of betamethasone, 10 mg of clotrimazole and 1 mg of gentamicin in the form of sulfate.

Triacutan Pharmacological properties
This pharmaceutical refers to a combination of corticosteroids and antibacterial drugs that are intended for use in dermatology.
In particular, betamethasone has a high glucocorticosteroid activity, and at the same time, a minimal mineralocorticoid effect. Produces anti-inflammatory, antipruritic, and vasoconstrictor effects.
Clotrimazole is effective in the fight against diseases caused by fungi of the genus “Candida”.
The antibiotic gentamicin has a broad spectrum of action due to its ability to inhibit 30S ribosomal subunits. In vitro tests have shown that the drug is highly effective against both gram-positive and gram-negative microorganisms, as well as indole-positive and indolegative bacteria.
Gentamicin is commonly used as the primary treatment for severe suppurative infections caused by gram-negative bacteria.
Since the drug is effective against a wide range of pathogenic flora, it can be used to treat diseases caused by various pathogens (mixed infection). If the pathogen is not identified, gentamicin is preferable to use, using it in combination with semi-synthetic penicillins, in particular, with such as ampicillin, carbenicillin.

Triacutan Indications
Because gentamicin has a broad spectrum of activity, this drug is used to treat cases of bacterial and fungal infections caused by microflora that are sensitive to corticosteroids and gentamicin. In particular, when:

  • eczema (atopic, children’s, coin-like);
  • anogenital and senile itching;
  • contact and other types of dermatitis;
  • mycoses of the skin, feet, epidermophytosis groin, trichophytosis.

You should not use the specified drug if the patient has had a previous hypersensitivity (allergy) with respect to one of the components that are part of the drug – both basic and auxiliary.
Also contraindicated for:

  • viral infections, incl. post-vaccination reactions, chickenpox;
  • viral skin infections (herpes, shingles, syphilis with skin manifestations);
  • common plaque psoriasis;
  • varicose veins;
  • mycoses of the skin;
  • ophthalmic diseases.

In pediatrics, it is used from 2 years of age. Until this age, gentamicin is used only for health reasons.

Application during pregnancy and lactation
It is strictly forbidden to use for the treatment of pregnant women in the first trimester of pregnancy, in the third and second – with caution, according to strict indications.
During treatment with this drug, breastfeeding should be suspended.

Method of administration and dosage
This drug is used by applying it in a thin layer to the entire affected area of ​​the skin twice a day – in the morning and before going to bed. In mild cases, it is enough to apply the cream once a day, in difficult cases, it is permissible to apply it more often.
The course of treatment lasts from several days to 3-4 weeks, depending on the severity of the disease, the patient’s response to the drug.

Corticosteroid overdose can cause:

  • suppression of pituitary-adrenal function;
  • secondary insufficiency of the adrenal glands;
  • manifestation of symptoms of hypercortisolism, including Cushing’s syndrome;
  • resistance to gentamicin drugs.

Recommended symptomatic treatment, gradual withdrawal of the drug.

Triacutan Side effects
The most common side effects are:

  • rash, increased sensitivity, hyperpigmentation;
  • skin irritation, erythema, itching;
  • dry skin, folliculitis, hypertrichosis, acne-like rash;
  • hypopigmentation, acne, rosacea-like dermatitis;
  • maceration of the skin, skin atrophy;
  • peeling of the skin, telangiectasia;
  • secondary infection.

Storage conditions and periods
This medicinal product is able to retain its medicinal properties for 3 years from the date of manufacture, which is usually indicated on the package.
The drug should be kept out of the reach of children. Storage temperature should not exceed 25 ° C.