Triftazin-Zdorovye (trifluoperazine) coated tablets 5 mg №50


Manufacturer: Ukraine

Psychotic disorders, including schizophrenia.

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Triftazin-Zdorovye (trifluoperazine) coated tablets 5 mg №50


active substance: 1 tablet contains trifluoperazine 5 mg;

excipients: lactose monohydrate; corn starch; microcrystalline cellulose; povidone; colloidal anhydrous silica; croscarmellose sodium; stearic acid; hypromellose; titanium dioxide (E 171); indigo carmine (E 132).

Dosage form

Film-coated tablets.

Main physical and chemical properties: film-coated tablets, from light blue to blue. Two layers are visible in cross section.

Pharmacotherapeutic group

Antipsychotics. Piperazine derivatives of phenothiazine.
ATX code N05A B06.

Pharmacological properties

It is an antipsychotic (neuroleptic). It has a pronounced antipsychotic, antiemetic effect. Also has alpha-adrenolytic, mild sedative and anticholinergic effects. It has a long-term and pronounced effect on productive mental symptoms (delirium, hallucinations). May cause extrapyramidal disorders.


Triftazin-Zdorovye is used:

  • with schizophrenia, other mental illnesses that occur with hallucinations, delirium, psychomotor agitation;
  • with vomiting of central genesis.


Triftazin-Zdorovye is not used:

  • if you are allergic to trifluoperazine, other components of the drug;
  • with suppression of the function of the central nervous system, coma;
  • with TBI;
  • with pathology of the kidneys, liver, hematopoietic organs with a violation of their functions;
  • with progressive systemic diseases of the spinal cord or brain;
  • with peptic ulcer of the duodenum, stomach in the acute phase;
  • with decompensated heart failure;
  • with severe arterial hypotension;
  • for diseases accompanied by the risk of thromboembolic complications;
  • with angle-closure glaucoma;
  • with prostatic hyperplasia;
  • with myxedema;
  • during pregnancy / lactation;
  • children under three years old.

Triftazin-Zdorovye is used with caution:

  • in the treatment of elderly patients;
  • with vomiting (may mask vomiting associated with drug intoxication);
  • with alcohol intoxication;
  • with Reye’s syndrome;
  • with cachexia;
  • with breast cancer;
  • with Parkinson’s disease;
  • with urinary retention;
  • with chronic diseases of the respiratory organs;
  • with epileptic seizures.

Application during pregnancy and lactation


Method of administration and dosage

The drug Triftazin-Zdorovye is taken orally after meals. The daily dose is divided into 2 – 3 doses.
The standard dose for the treatment of anxiety conditions is 1 mg 2 times / day; psychotic disorders – 2-5 mg 2 times / day. To obtain the optimal effect, the dose is gradually increased to 15-20 mg / day. The maximum is 40 mg / day.
Children 6-12 years old in the treatment of psychotic disorders are shown 1 mg 1-2 times / day, if necessary – 4 mg / day. Children over 12 years old are shown 5-6 mg / day.
When vomiting in adults, appoint 1-2 mg 2 times / day.
For elderly patients, the dose is reduced.


Symptoms: areflexia / hyperreflexia, cardiotoxic effects (heart failure, arrhythmia, drop in blood pressure, tachycardia, shock, ventricular fibrillation, changes in the QRS complex, cardiac arrest), blurred vision, neurotoxic effects (agitation, confusion, disorientation, convulsions , stupor, coma), dry mouth, mydriasis, hyperpyrexia / hypothermia, muscle stiffness, pulmonary edema, vomiting, respiratory depression.
Symptomatic treatment is carried out. Control of the function of the cardiovascular system, respiration, central nervous system, thermometry, psychiatric consultation.

Side effects:

  • Neurological disorders: drowsiness, insomnia, dizziness, mental indifference, extrapyramidal disorders (dyskinesia, akinetic phenomena, tremor, akathisia, hyperkinesis, autonomic disorders), convulsions, neuroleptic malignant syndrome.
  • Ophthalmic disorders: paresis of accommodation, retinopathy, opacity of the cornea or lens.
  • Genitourinary disorders: urinary retention, frigidity, decreased potency, decreased libido, priapism, ejaculation disorders, oliguria.
  • Endocrine disorders: hypo / hyperglycemia, amenorrhea, glucosuria, hyperprolactinemia, galactorrhea, dysmenorrhea, breast swelling, gynecomastia, mastalgia, weight gain.
  • Digestive disorders: dry mouth, constipation, decreased appetite, bulimia, vomiting, gastralgia, diarrhea, cholestatic jaundice.
  • Changes in laboratory parameters: thrombocytopenia, increased blood clotting, lymph / leukopenia, anemia, agranulocytosis, eosinophilia, pancytopenia, false positive pregnancy test.
  • Cardiovascular disorders: tachycardia, orthostatic hypotension, arrhythmia, lengthening of the Q – T interval, inversion or decrease in the T wave. Allergic reactions: urticaria, skin rash, angioedema.
  • Others: melanosis, pigmentation of the conjunctiva, skin, discoloration of the cornea and sclera, decreased tolerance to high temperatures (heatstroke may develop).