Troxevazin gel 2% 100 g. tube


Troxevasin gel is used for the symptomatic treatment of the following diseases: venous insufficiency; pre-varicose and varicose syndrome; superficial thrombophlebitis, phlebitis and postphlebitis conditions; complex treatment of hemorrhoidal disease; swelling and pain with injuries and varicose veins; muscle krampi (convulsive contraction of the calf muscles).



Composition and form of release
Troxevasin is produced in the form of a gel for external use and capsules of 300 mg.
1 g of the gel contains 20 mg of troxerutin, as well as auxiliary substances: carbomer 6 mg, trolamine (triethanolamine) 7 mg, disodium edetate 0.5 mg, benzalkonium chloride 1 mg, purified water 965.5 mg.
One capsule contains an active substance – 300 mg of troxerutin, excipients – magnesium stearate, quinoline yellow dye E104, lactose monohydrate, sunset yellow dye E110, gelatin, titanium dioxide E171.
Troxevasin is a blood vessel strengthening drug. Its active ingredient is a flavonoid (rutin derivative). Possesses P-vitamin activity, has a venoprotective (protects the veins), venotonic (increases the tone of the venous wall), decongestant, anticoagulant, anti-inflammatory and antioxidant effects. Reduces permeability, fragility of small vessels – capillaries, increases the tone of their walls. Increases the density of the walls of blood vessels, reduces the exudation of the liquid part of the plasma (diapedesis). Reduces the severity of inflammation in the vascular wall, limits the adhesion of platelets to its surface.
When the gel is applied to the affected area, the acting molecules quickly penetrate through the skin structures – after 30 minutes they are found in the connective tissue part of the skin, and after 2-5 hours in the subcutaneous tissue.
After oral administration, about 10-15% of the active substance is absorbed. The maximum concentration in the blood is observed after 2 hours, the therapeutic level will remain for 8 hours. The drug is excreted by the liver, partially – unchanged with urine and bile.
Indications for the use of the gel:

  • with varicose veins;
  • with chronic venous insufficiency with symptoms such as: pain, swelling in the legs, a feeling of heaviness, fatigue, fullness of the legs, spider veins, nets, paresthesia (feeling of numbness, tingling, creeping, creeping, burning), convulsions;
  • with thrombophlebitis;
  • with periphlebitis;
  • with varicose dermatitis;
  • in case of pain, edema of a traumatic nature (due to bruises, sprains, injuries).

Indications for the use of Troxevasin capsules:

  • with postphlebitic syndrome;
  • with chronic venous insufficiency;
  • with trophic disorders due to varicose veins, trophic ulcers;
  • for hemorrhoids with pain, exudation, itching, bleeding;
  • after sclerotherapy of veins, removal of varicose veins (auxiliary treatment);
  • with venous insufficiency, hemorrhoids in pregnant women, starting from the second trimester;
  • with retinopathy (retinal damage) in patients with diabetes mellitus, atherosclerosis, arterial hypertension.

Troxevasin gel cannot be prescribed for allergies to components, violation of the integrity of the skin at the site of the intended application.
Troxevasin capsules are contraindicated in case of allergy to components, allergy to rutosides, in the first trimester of pregnancy, in case of gastric / duodenal ulcer, chronic gastritis in the acute phase, up to three years of age. Use this medicine with caution (especially for a long time) in case of kidney failure, in children aged 3 to 15 years.
Application during pregnancy and lactation
It is allowed to use this medicine in the form of capsules in the II and III trimesters of pregnancy and during lactation if the expected benefit to the mother outweighs the risk to the fetus / child.
There are no data regarding undesirable effects on the course of pregnancy, fetal development, the condition of the newborn when using the gel.
Method of administration and dosage
The gel is used externally. It is applied to the affected area twice a day (in the morning and in the evening), rubbing with light finger movements until completely absorbed. It is allowed, if necessary, to apply gel under bandages, elastic stockings.
To enhance the effect, it is recommended to combine the use of the gel with the administration of Troxevasin capsules.
If the symptoms of the disease do not go away within 6-7 days of daily use of the drug or worsen, you should consult a doctor who will prescribe further treatment and determine the duration of the course of treatment.
Troxevasin capsules are taken orally during meals. The capsule should be swallowed whole, washed down with water. At the initial stage of treatment, 1 capsule (300 mg) x 3 times / day is usually prescribed. The drug effect usually develops within two weeks, after which the treatment is continued at the same dose or reduced to the minimum maintenance dose – 600 mg, or the treatment is suspended (while the effect obtained remains for at least four weeks). The standard course of treatment is 3-4 weeks on average, the need for a longer treatment is determined individually.
In diabetic retinopathy, 900–1800 mg / day is usually prescribed.
The effect of the drug is enhanced by the simultaneous intake of vitamin C (ascorbic acid).

In case of an overdose of capsules, the following signs of poisoning may appear: agitation, urge to vomit, headache, a feeling of blood rush to the face.
Overdose treatment: it is necessary to flush the stomach (if lavage is impossible, vomiting should be artificially induced), take any enterosorbent (for example, activated carbon), if necessary, carry out symptomatic treatment.
Due to the external method of using the gel, there is no danger of an overdose. In case of accidental use of a large amount of gel inside, it is necessary to carry out general measures for removing the drug from the body: gastric lavage, the use of saline laxatives, if necessary, symptomatic and supportive treatment. Peritoneal dialysis should be performed if indicated.
Side effects
When treating with gel, allergic skin reactions can be observed in the form of urticaria (urticaria), eczema, dermatitis.
When treating with capsules, nausea, heartburn, diarrhea (frequent and loose stools), headache, erosive and ulcerative lesions of the gastrointestinal mucosa, “hot flushes” of blood to the face are possible. There is a low probability of developing an allergic reaction, manifested by itching, redness of the skin, urticaria, skin irritation, shortness of breath. More severe allergic manifestations are not excluded: Quincke’s edema (rapidly developing edema of the eyes, face or part of it, lips, larynx – with impaired airway patency), anaphylactic shock (manifested by severe itching of the skin, quickly spreading over the skin, a sharp drop in blood pressure, vomiting , loose stools, laryngeal edema, disturbance of the vital organs, noisy and labored breathing, pallor or cyanosis of the skin, a sharp narrowing of the bronchi, larynx, leading to acute difficulty in breathing, loss of consciousness).
Storage conditions and periods
The drug must be stored and transported in its original packaging in compliance with the temperature regime (15–25 ° C), low humidity, and the absence of direct sunlight. The maximum shelf life of the tablets is indicated on the packaging. The shelf life of capsules is 5 years, a gel in an aluminum tube is 5 years, in a plastic (laminate) tube – 2 years. Parents have a responsibility to ensure the safety of their children by restricting access to medication.