Truxal coated tablets 50 mg. №50


Schizophrenia and other psychoses with psychomotor anxiety, anxiety and agitation; treatment of withdrawal from alcoholics and drug addicts; depressive syndromes, neurosis, psychosomatic disorders, accompanied by anxiety, tension, restlessness, insomnia, sleep disturbance; epilepsy and oligophrenia associated with mental disorders, such as eretism, agitation, mood lability and behavior disorders; chronic pain (in addition to analgesics); geriatrics: hyperactivity, agitation, irritability, confusion, anxiety, impaired behavior and sleep.



Composition and form of release
The active ingredient is chlorprothixene hydrochloride, auxiliary components, including lactose, talc. It is produced in the form of tablets 50  milligrams.
It is used to treat psychosis (without a symptom of depression of consciousness), including mania and schizophrenia, as well as for the treatment of withdrawal symptoms, age-related hyperactivity, neuroses, insomnia, depression, pain syndrome, psychosomatic disorders, behavioral disorders in pediatrics.
The active ingredients of the drug are able to block dopamine receptors, due to which the mechanism of sedation is triggered, antidepressant and analgesic effects are manifested. It also has adrenergic blocking, antihistamine activity, lowers blood pressure.
It is contraindicated to use in case of poisoning with barbiturates, opiates, alcohol, allergies to the substances that make up it. It is not prescribed for parkinsonism, diabetes mellitus, atherosclerosis, tendency to collapse, epilepsy, in childhood.
This pharmaceutical should not be used if the patient suffers from insufficiency of the heart, kidneys, liver, and finally, with prostatitis.
Application during pregnancy and lactation
Not recommended.
Method of administration and dosage
The dosage is prescribed and adjusted by the doctor after an individual assessment of the patient’s condition. Treatment starts with a small dosage, then gradually increases until it is optimally effective.
Schizophrenia, mental states, mania: the starting dose is 50-100 mg per day, with a gradual increase to the optimal 300 mg. The maximum daily dose is 1200. The maintenance dose is 100-200 mg. The application is divided into 2-3 doses during the day, with a large dose in the evening.
Withdrawal symptoms: 500 mg per day, treatment lasts for one week. After reaching the therapeutic effect, the dose is gradually reduced. The maintenance dose is 100 mg, which are taken in parts (in the morning and afternoon – 25 mg each, in the evening – 50 milligrams). After some time, the dose can be reduced.
Depression, neuroses, psychosomatic disorders: from 25 to 100-150 mg per day. Reception is also divided into 3 parts.
Sleep disturbances: 25 mg at night. Epilepsy, oligophrenia: 100-125 mg. Chronic pain, a combination with analgesics is possible: the initial dose is 75-100 mg, the dosage can be gradually increased to 200-300 mg.
Overdose can cause drowsiness, coma, shock, hypothermia, hyperthermia, kidney damage. Symptomatic therapy is prescribed.
Side effects
Taking this drug can cause side effects in the form of drowsiness, jaundice, gynecomastia in men, hyperhidrosis, weakening of potency, libido, dysmenorrhea, drop in blood pressure, tachycardia, seizures. In rare cases, excessive weight gain, constipation, anemia, galactorrhea, benign leukopenia, and dysmenorrhea have occurred.
Storage conditions and periods
Shelf life is 3 years, in all other cases – 5 years when stored at a temperature not exceeding 25 ° C.