Ureotop (urea) ointment 12% 50 g.


For the treatment of neurodermatitis (including in the elderly), as well as an adjuvant in the treatment of ichthyosis.



Composition and form of release
Main active ingredient: urea.
The auxiliary components included in the composition: cetylpyridinium chloride, propylene glycol, mineral oil, cetostearyl alcohol, purified water.
The drug is created in the form of an ointment, in tubes of 50 grams. 1 g of ointment contains 120 mg of urea.
Pharmacological properties
This drug belongs to the group of topical drugs used in dermatology to soften keratinized tissues and protect the skin.
The main active ingredient is urea. This component is carbonic acid diamide.
It has keratolytic, antipruritic, antibacterial, antifungal and hydrating effects.
Topical use of this drug leads to a decrease in excessive dehydration, reducing hypercaretosis.
There is a significant softening and moisturizing of the skin. The drug has the ability to increase elasticity and improve epithelization of the upper layers of the dermis, damage to its surface.
At 10% concentration, urea produces bactericidal and fungicidal effects. The drug owes its mechanism of action to the presence of cytylpyridinium chloride in urea, which is an integral part of this drug.
It also has some local anesthetic effect, which also explains its antiallergic effect.
It is used to treat certain skin diseases characterized by dehydration and increased formation of keratinized epithelium.

  •  neurodermatitis, including in the elderly;
  •  ichthyosis, as an aid.

The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or to one of the auxiliary components.
It is also contraindicated for use in dermatoses, which are characterized by increased exudation, as well as in acute inflammatory processes on the skin.
Simultaneous use with other drugs can cause an increase in the absorption of the latter, especially corticosteroids.
Should not be used concurrently with other drugs that contain urea.
Avoid getting the drug on mucous surfaces and in the eyes. In case of contact with eyes, rinse with plenty of warm water.
Avoid getting the drug on healthy skin areas.
There is no data on the safety of use in pediatric practice.
Application during pregnancy and lactation
This drug is contraindicated in pregnant women.
If it is necessary to take the drug during breastfeeding, lactation is suspended.
Method of administration and dosage
This drug is used externally.
The dose depends on the degree and area of ​​skin lesions.
Usually, the ointment is applied in a thin layer 2 times a day. Applying an occlusive dressing will enhance the effect of the application.
The duration of treatment is usually 1 to 3 weeks, depending on the type and severity of the disease. Determined by the attending physician.
Overdose has not been recorded and is unlikely due to minor toxicity.
If accidentally swallowed, seek medical attention.
Increased side effects are possible.
Side effects
Some local side effects may occur with this drug. In particular, a burning sensation may occur at the site of application of the ointment, especially when applying an occlusive dressing, which quickly passes.
Hypersensitivity reactions may develop in case of allergies.
In particular, there may be observed:

  •  nausea, vomiting, diarrhea, abdominal pain;
  •  allergic reactions, incl. allergic urticaria.

Side effects usually go away on their own after drug withdrawal.
Storage conditions and periods
The shelf life is 3 years. After opening the tube, the shelf life is 6 months.
The storage temperature should not exceed 25 ° C.