Symptomatic treatment of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis, as well as in other diseases of the musculoskeletal system accompanied by pain (for example, humerus periarthritis or extra-articular rheumatism). As an analgesic in conditions accompanied by pain (including lumbar pain, toothache, and primary (functional) dysmenorrhea).
Composition and form of release
The active substance in this medicine is aceclofenac.
Zerodol is available in the form of tablets (100 mg).
It is an analgesic and anti-inflammatory drug. The drug also has an antipyretic effect. It suppresses the production of substances that cause pain, edema, secretion of inflammatory fluid in the site of inflammation. In rheumatic diseases helps to alleviate pain, eliminate swelling, stiffness of the joints, allowing to significantly improve their condition. Application after injuries, in the postoperative period helps to reduce inflammatory hypostasis, painful discomfort.
Zerodol is prescribed to reduce pain, the severity of inflammatory phenomena in diseases of the musculoskeletal system, including rheumatoid, juvenile, psoriatic arthritis, gouty arthritis, ankylosing spondylitis, osteoarthritis, bursitis, tendovaginitis. Also to eliminate pain in cancer, migraine, sciatica (sciatic nerve damage), ossalgia (bone pain), lumbago (low back pain, shots), toothache, arthralgia (joint pain), neuralgia, radiculitis, myalgia (muscle) pain), biliary / renal colic, pain after surgery, trauma, algodysmenorrhea (painful menstruation), infectious and inflammatory processes of the ENT organs (otitis, pharyngitis, tonsillitis), fever.
Zerodol should not be used:
- in case of intolerance to the main, excipients, allergies to other NSAIDs (nonsteroidal anti-inflammatory drugs);
- with exacerbation of diseases of the stomach or intestines (erosive-ulcerative nature);
- at bleeding;
- at disturbance of hematopoiesis, disturbance of blood coagulation (including hemophilia);
- with aspirin asthma;
- to children.
It is used with caution in bronchial asthma, congestive heart failure, liver / kidney disorders, inflammatory bowel disease, after major surgery (including coronary artery bypass grafting), the elderly.
Use during pregnancy and breastfeeding
The drug suppresses the production of prostaglandins, so it can adversely affect the course of pregnancy, fetal development. Therefore, Zerodol should not be prescribed during pregnancy.
The active substance may be excreted in human milk, so Zerodol should not be used during breast-feeding.
Method of application and dose
Zerodol tablets are administered orally.
The standard dose is 100 mg 1-2 times / day.
The tablet is taken after or during a meal.
Overdose is manifested by dizziness, dizziness, vomiting, headache, respiratory distress, bleeding, liver / kidney dysfunction.
In case of overdose, it is necessary to stop using this drug and seek medical help.
Nervous system disorders: cephalgia (headaches), sleep disorders, anxiety, depression, convulsions, drowsiness, aseptic meningitis, nightmares.
Digestive system disorders: abdominal pain, dry mouth, bloating, diarrhea / constipation, nausea, peptic ulcer, jaundice, esophageal lesions, hepatitis, blood in the stool, liver necrosis, cirrhosis, colitis, pancreatitis.
Perception disorders: tinnitus, double vision, blurred vision, hearing loss, taste disturbance.
Disorders of the genitourinary system: edema, protein in the urine, oliguria (decreased urine output), blood in the urine, nephritis, renal failure.
Skin changes: rash, eczema, alopecia (hair loss), toxic dermatitis, hives, itching, small hemorrhages, photosensitivity (sun intolerance).
Hematopoietic disorders: eosinophilia, anemia, leukopenia, thrombocytopenic purpura, agranulocytosis, thrombocytopenia.
Cardiac disorders: increased blood pressure, heart failure (congestive heart failure), extrasystole, sternal pain, heart attack.
Allergy: swelling of the lips, tongue, vasculitis (inflammation of blood vessels).
Respiratory disorders: bronchospasm, cough, pneumonitis, laryngeal edema.
Conditions and terms of storage
At 15–25 ° C no more than 2 years.