Treatment of erectile dysfunction characterized by the inability to achieve or maintain the erection of a penis necessary for a successful sexual act. Sexual arousal is required for Zidena’s effective action.
Composition and form of release
Main active substances: 1 film-coated tablet contains udenafil 100 mg or 200 mg.
Auxiliary components: lactose, corn starch, hydroxypropylcellulose, colloidal silicon dioxide, talc, magnesium stearate, hypromellose, titanium dioxide, yellow sunset FCF.
This pharmacological drug belongs to a group of drugs for the correction of erectile dysfunction.
The drug selectively reversibly inhibits cyclic guanosine monophosphate, a specific type V phosphodiesterase.
It does not show a direct relaxing effect on the corpus cavernosum. However, sexual stimulation enhances the relaxation effect by inhibiting PDE-5, which is responsible for the breakdown of cGMP in the corpus cavernosum.
After that, the smooth muscles of the arteries relax and blood flows to the penis, which leads to an erection. The drug is effective in the absence of sexual arousal.
The drug is effective for up to 24 hours.
The primary effect is observed 30 minutes after taking the drug.
The drug is prescribed for the treatment of erectile dysfunction, characterized by the inability to achieve or maintain an erection of the penis, necessary for successful sexual intercourse.
The drug in question is contraindicated in cases where the patient has a pronounced hypersensitivity (allergy) to the main or to one of the auxiliary components.
The drug is contraindicated in the following conditions:
hereditary degenerative diseases of the retina (including retinitis pigmentosa);
severe hepatic or renal failure;
the presence of congenital syndrome of QT prolongation or increase in QT interval due to medication;
unstable angina or severe heart failure;
stroke, myocardial infarction or coronary artery bypass grafting in the last 6 months;
use of strong cytochrome P450 inhibitors (HIV protease inhibitor indinavir or ritonavir, concomitant use of the drug with other drugs for the treatment of erectile dysfunction).
The drug is not used in pediatrics.
Use during pregnancy and breastfeeding
This drug is not recommended for use by pregnant women – only under strict indications determined by the attending physician.
If it is necessary to take the drug during breastfeeding, lactation is suspended.
Method of application and dose
The drug is taken regardless of food intake, one table. 100 mg per day for about 30 minutes. to the alleged sexual activity. The dose can be increased with caution to 200 mg, after careful evaluation of all adverse events that occurred after taking 100 mg of the drug. The maximum recommended number of applications is once a day.
With increasing dose, the frequency of adverse events increases: headache, flushing.
The drug is usually well tolerated if used in the recommended doses and the mode of administration is observed.
Allergies may occur in case of individual intolerance. In particular, the following can be observed:
chest pain, abdominal pain, fatigue, flushing, chest discomfort;
dizziness, stiffness of the occipital muscles, paresthesia;
blurred vision, eye pain, chromatopsia;
shortness of breath, dryness of the nasal mucosa;
swelling of the face or eyes, hives, itching;
Conditions and terms of storage
Shelf life – up to 3 years from the date of manufacture indicated on the package. Do not exceed the shelf life.
Storage temperature should not exceed 25 ° C. Temperature deviations can change the properties of the drug, so it should always be stored in the original packaging.