Zilola (levocetirizine) coated tablets 5 mg. №28


Symptomatic treatment of allergic rhinitis, including year-round allergic rhinitis; chronic idiopathic urticaria.



Composition and form of release
Active ingredient: levocetirizine dihydrochloride.
Zilola is available in the form of tablets (5 mg).
Pharmacological properties
Is an anti-allergic drug. Contains the active R-enantiomer of cetirizine, belonging to the group of histamine antagonists. Its action is due to its ability to block histamine (h1) receptors. Affects the histamine-dependent phase of allergy development, reducing vascular permeability, eosinophil migration, limiting the release of other inflammatory mediators. The drug prevents the development or alleviates the course of allergies, relieving itching, swelling, redness and other manifestations.
Zilola is prescribed for symptomatic treatment (elimination of manifestations):

  • year-round (persistent) allergic rhinitis, accompanied by nasal congestion, sneezing, rhinorrhea (watery discharge), tearing, redness of the conjunctiva;
  • seasonal (intermittent) allergic rhinitis (hay fever, hay fever);
  •  СIU (chronic idiopathic urticaria);
  •  allergic dermatosis, accompanied by itching, rashes.

Do not use Zilola:

  •  in case of intolerance to levocetirizine, any other component of the drug (see the list in the insert);
  •  in case of intolerance to piperazine derivatives;
  • at a chronic kidney disease at the IV (terminal) stage.

Use during pregnancy and breastfeeding
Zilola is not prescribed to pregnant or nursing mothers (cetirizine passes into milk).
Method of application and dose
The tablets are administered orally (swallowed). Admission does not depend on food.
Standard dosage: adults, children older than 6 years are prescribed 5 mg (one tablet) x1 times / day
The maximum dose that can be taken per day is 10 mg (2 tablets).
The duration of use depends on the indications. Treatment is stopped when the symptoms disappear.
In the case of a stable course, continuous therapy may be prescribed during contact with allergens. In chronic forms of the disease, the duration of treatment can be up to 1 year.
Symptoms of overdose: in adults – drowsiness, agitation, in children – increased irritability with the transition to drowsiness.
Treatment of overdose: shortly after taking the drug consider the need for gastric lavage. It is recommended to take sorbents (activated charcoal), symptomatic, supportive therapy. Hemodialysis is not used.
Side effects

Mental disorders:

suicidal thoughts, depression, insomnia, agitation, sleep disturbances, hallucinations, aggression.
Cardiovascular disorders:

tachycardia, palpitations.
Visual impairment:

decreased acuity, blurred vision.
Hepatobiliary disorders:

inflammatory changes of the liver (hepatitis).
Disorders of balance and hearing:

Urinary disorders:

urinary retention, dysuria.
Immune disorders:

allergic reactions, including anaphylaxis, angioneurotic edema.
Changes in laboratory indicators of blood:

decrease in number of thrombocytes (thrombocytopenia), deviations of indicators of functional liver tests.
Respiratory disorders:

shortness of breath.
Digestive disorders:

diarrhea / constipation, nausea, dry mouth, abdominal pain / discomfort.
Skin changes:

angioneurotic edema, pruritus, rash, persistent rash, urticaria.
Musculoskeletal disorders:

myalgia (muscle pain).
Metabolic disorders:

weight gain, increased appetite, edema.
Conditions and terms of storage
Zilola can be stored for no more than 2 years in the original packaging.