Zocardis (zofenopril calcium) coated tablets 7.5 mg. №28


Treatment of essential hypertension of mild to moderate severity. Acute myocardial infarction. Treatment of patients with acute myocardial infarction within the first 24 hours with signs or symptoms (or without) of heart failure with stable hemodynamics, provided that they have not been treated with thrombolytic therapy.



Composition and form of release

Tablets that are coated with an enteric film. Each tablet contains 7.5 mg of zofenopril calcium. The drug is sold in 7 tablets, placed in blisters of 1 or 2 blisters in a cardboard box.


It is used in the treatment of essential hypertension of mild or moderate severity.

In addition, it is used in the first 24 hours in the treatment of acute myocardial infarction, which is accompanied by unaccompanied signs of acute heart failure and is characterized by stable hemodynamics, but only if the patient has not received thrombolytic treatment.


The drug should not be used if the patient has previously been diagnosed with intolerance to zofenopril calcium and other ACE inhibitors. The drug should be discontinued if the patient has previously developed ACE inhibitors while developing angioneurotic edema or has a history of hereditary or idiopathic angioneurotic edema.

The drug is not prescribed if the patient suffers from severe liver dysfunction. Absolute contraindications to the use of the drug are pregnancy and lactation, bilateral bilateral renal artery stenosis or unilateral if the patient has one kidney.

Use during pregnancy and breastfeeding


Method of application and dose

The drug is intended for oral administration regardless of food. The dose of the drug is selected by the doctor individually taking into account the therapeutic response of the patient’s body to its introduction.

In the treatment of hypertension, the dose is selected taking into account the level of blood pressure. The dose is increased at intervals of at least four weeks.

Patients who do not show symptoms of water or salt depletion in the initial dosage receive 15 mg of the drug once a day. The dosage is increased until the blood pressure level normalizes. In most cases, the effective therapeutic dose is 30 mg. The highest daily dose is 60 mg.


The use of the drug in high doses may cause the patient to develop severe hypotension, stupor, shock, bradycardia, electrolyte disturbances and renal dysfunction.

At detection of symptoms of acute poisoning the patient is shown constant control of level of electrolytes and creatinine in blood serum, gastric lavage and appointment of correct treatment. In severe cases, the introduction of drugs to increase blood plasma volume is indicated.

Side effects

Dizziness, headache, cough, dyspeptic disorders, angioneurotic edema, local allergic reactions, muscle cramps, fatigue, asthenia, hypoglycemia, depression, change of consciousness, insomnia, disorientation, paresthesia, disturbance of taste, disturbance of taste ears and dry mouth.

Conditions and terms of storage

Zocardis 7.5 Mg should be stored in places that are as inaccessible to children and protected from light and moisture. The shelf life of the drug does not exceed 3 years.